| Date | Opponent | Location | Time/Result | TV |
| Sept. 5 | Ball State | Columbus | TBA | TBA |
| Sept. 12 | at Texas | Austin, Texas | 7:30 p.m. | ABC |
| Sept. 19 | Kent State | Columbus | TBA | TBA |
| Sept. 26 | Illinois | Columbus | TBA | TBA |
| Oct. 3 | at Iowa | Iowa City, Iowa | TBA | TBA |
| Oct. 10 | Maryland | Columbus | TBA | TBA |
| Oct. 17 | at Indiana | Bloomington, Ind. | TBA | TBA |
| Oct. 31 | at USC | Los Angeles, Calif. | TBA | TBA |
| Nov. 7 | Oregon | Columbus | TBA | TBA |
| Nov. 14 | Northwestern | Columbus | TBA | TBA |
| Nov. 21 | at Nebraska | Lincoln, Neb. | TBA | TBA |
| Nov. 28 | Michigan | Columbus | Noon | Fox |
| Date | Opponent | Location | Time/Result | TV |
| Sept. 4 | Bowling Green | Columbus | TBA | TBA |
| Sept. 11 | New Hampshire | Columbus | TBA | TBA |
| Sept. 18 | Alabama | Columbus | TBA | TBA |
| TBA | Michigan State | Columbus | TBA | TBA |
| TBA | Purdue | Columbus | TBA | TBA |
| TBA | Nebraska | Columbus | TBA | TBA |
| TBA | USC | Columbus | TBA | TBA |
| TBA | at Michigan | Ann Arbor, Mich. | TBA | TBA |
| TBA | at Minnesota | Minneapolis, Minn. | TBA | TBA |
| TBA | at Northwestern | Evanston, Ill. | TBA | TBA |
| TBA | at Oregon | Eugene, Ore. | TBA | TBA |
| TBA | at Rutgers | Piscataway, N.J. | TBA | TBA |
| Date | Opponent | Location | Time/Result | TV |
| Sept. 2 | Buffalo | Columbus | TBA | TBA |
| Sept. 9 | at Alabama | Tuscaloosa, Ala. | TBA | TBA |
| Sept. 16 | Northern Illinois | Columbus | TBA | TBA |
| TBA | Michigan | Columbus | TBA | TBA |
| TBA | Minnesota | Columbus | TBA | TBA |
| TBA | Rutgers | Columbus | TBA | TBA |
| TBA | Washington | Columbus | TBA | TBA |
| TBA | Wisconsin | Columbus | TBA | TBA |
| TBA | at Illinois | Champaign, Ill. | TBA | TBA |
| TBA | at Maryland | College Park, Md. | TBA | TBA |
| TBA | at Penn State | State College, Pa. | TBA | TBA |
| TBA | at UCLA | Pasadena, Calif. | TBA | TBA |
| Date | Opponent | Location | Time/Result | TV |
| Sept. 14 | at Georgia | Athens, GA | TBA | TBA |
| Date | Opponent | Location | Time/Result | TV |
| Aug. 30 | Georgia | Columbus | TBA | TBA |
| Date | Opponent | Location | Time/Result | TV |
| Sept. 11 | at Oregon | Eugene, OR | TBA | TBA |
| Date | Opponent | Location | Time/Result | TV |
| Sept. 10 | Oregon | Columbus | TBA | TBA |
| Date | Opponent | Location | Time/Result | TV |
| Sept. 15 | Boston College | Columbus | TBA | TBA |
| Date | Opponent | Location | Time/Result | TV |
| Sept. 13 | at Boston College | Chestnut Hill, MA | TBA | TBA |
