| Date | Opponent | Location | Time/Result | TV |
|---|---|---|---|---|
| Nov. 1 | Chaminade (Exhibition) | Columbus | W, 101-57 | B1G+ |
| Nov. 7 | Robert Morris | Columbus | W, 91-53 | B1G+ |
| Nov. 10 | Charleston Southern | Columbus | W, 82-56 | BTN |
| Nov. 16 | Eastern Illinois | Columbus | W, 65-43 | BTN |
| Nov. 21 | San Diego State | Lahaina, HI | L, 88-77 | ESPN |
| Nov. 22 | Cincinnati | Lahaina, HI | W, 81-53 | ESPN |
| Nov. 23 | Texas Tech | Lahaina, HI | W, 80-73 | ESPN |
| Nov. 30 | Duke | Durham, NC | L, 81-72 | ESPN |
| Dec. 3 | St. Francis | Columbus | W, 96-59 | BTN |
| Dec. 6 | Rutgers | Columbus | W, 67-66 | ESPN2 |
| Dec. 17 | North Carolina | New York, NY | L, 89-84 (OT) | CBS |
| Dec. 21 | Maine | Columbus | W, 95-61 | BTN |
| Dec. 29 | Alabama A&M | Columbus | W, 90-59 | BTN |
| Jan. 1 | Northwestern | Evanston, Ill. | W, 73-57 | BTN |
| Jan. 5 | Purdue | Columbus | L, 71-69 | FS1 |
| Jan. 8 | Maryland | College Park, Md. | L, 80-73 | ESPN |
| Jan. 12 | Minnesota | Columbus | L, 70-67 | FS1 |
| Jan. 15 | Rutgers | Piscataway, N.J. | L, 68-64 (OT) | BTN |
| Jan. 18 | Nebraska | Lincoln, Neb. | L, 63-60 | BTN |
| Jan. 21 | Iowa | Columbus | 2 p.m. | FOX |
| Jan. 24 | Illinois | Champaign, Ill. | 7 p.m. | ESPN |
| Jan. 28 | Indiana | Bloomington, Ind. | 8 p.m. | FOX |
| Feb. 2 | Wisconsin | Columbus | 7 p.m. | FS1 |
| Feb. 5 | Michigan | Ann Arbor, Mich. | 1 p.m. | CBS |
| Feb. 9 | Northwestern | Columbus | 8 p.m. | FS1 |
| Feb. 12 | Michigan State | Columbus | 1 p.m. | CBS |
| Feb. 16 | Iowa | Iowa City, Iowa | 9 p.m. | ESPN2 |
| Feb. 19 | Purdue | West Lafayette, Ind. | 1 p.m. | CBS |
| Feb. 23 | Penn State | Columbus | 6:30 p.m. | FS1 |
| Feb. 26 | Illinois | Columbus | 12 p.m. | CBS |
| March 1 | Maryland | Columbus | 7 p.m. | BTN |
| Match 4 | Michigan State | East Lansing, Mich. | TBA | ESPN |
| March 8-12 | Big Ten Basketball Tournament | Indianapolis, Ind. | TBA | TBA |